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Metformin Inhibits Tumorigenesis and Tumor Growth of Breast Cancer Cells by Upregulating miR-200c but Downregulating AKT2 Expression

Background: Metformin has been reported to inhibit the growth of various types of cancers, including breast cancer. Yet the mechanisms underlying the anticancer effects of metformin are not fully understood. Growing evidence suggests that metformin's anticancer effects are mediated at least in...

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Detalles Bibliográficos
Autores principales: Zhang, Jiali, Li, Gefei, Chen, Yuan, Fang, Lei, Guan, Chen, Bai, Fumao, Ma, Mengni, Lyu, Jianxin, Meng, Qing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556649/
https://www.ncbi.nlm.nih.gov/pubmed/28819383
http://dx.doi.org/10.7150/jca.19858