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The comparison of EGFR-TKI failure modes and subsequent management between exon 19 deletion and exon 21 L858R mutation in advanced non-small-cell lung cancer

Background: Advanced non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion (19 Del) and exon 21 L858R mutation (L858R) might be distinct diseases. Therefore, it is necessary to take EGFR mutation subgroups into consideration for making choices of subsequent...

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Detalles Bibliográficos
Autores principales: Zhang, Yaxiong, Chen, Gang, Chen, Xi, Fang, Wenfeng, Gao, Fei, Yang, Yunpeng, Zhao, Yuanyuan, Ma, Yuxiang, Hong, Shaodong, Zhang, Zhonghan, Miao, Siyu, Wu, Manli, Huang, Xiaodan, Luo, Youli, Zhou, Cong, Gong, Run, Huang, Yan, Chen, Likun, Zhou, Ningning, Zhao, Hongyun, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556650/
https://www.ncbi.nlm.nih.gov/pubmed/28819384
http://dx.doi.org/10.7150/jca.19867