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Comparison of Prostaglandin E1 and Sildenafil Citrate Administration on Skin Flap Survival in Rats

BACKGROUND: Alprostadil and sildenafil are known vasodilators used independently to improve flap survival in animal models. In this study, we investigate whether these agents act synergistically to decrease flap necrosis in rat models. METHODS: After acclimation period, 4 groups of 10 male white rat...

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Detalles Bibliográficos
Autores principales: Choi, Ji-An, Lee, Keun-Cheol, Kim, Min-Su, Kim, Seok-Kwun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Cleft Palate-Craniofacial Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556853/
https://www.ncbi.nlm.nih.gov/pubmed/28913226
http://dx.doi.org/10.7181/acfs.2015.16.2.73