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Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

BACKGROUND: The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with progression to end-stage renal disease (ESRD) in patients for whom prognosis could...

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Detalles Bibliográficos
Autores principales: Paunas, Teodora Ioana Flavia, Finne, Kenneth, Leh, Sabine, Marti, Hans-Peter, Mollnes, Tom Eirik, Berven, Frode, Vikse, Bjørn Egil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557313/
https://www.ncbi.nlm.nih.gov/pubmed/28814945
http://dx.doi.org/10.1186/s12014-017-9165-x