Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis

Engrailed 1 (En1) and 2 (En2) code for closely related homeoproteins acting as transcription factors and as signaling molecules that contribute to midbrain and hindbrain patterning, to development and maintenance of monoaminergic pathways, and to retinotectal wiring. En2 has been suggested to be an...

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Detalles Bibliográficos
Autores principales: Soltani, Asma, Lebrun, Solène, Carpentier, Gilles, Zunino, Giulia, Chantepie, Sandrine, Maïza, Auriane, Bozzi, Yuri, Desnos, Claire, Darchen, François, Stettler, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557355/
https://www.ncbi.nlm.nih.gov/pubmed/28809922
http://dx.doi.org/10.1371/journal.pone.0181350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557355/
https://www.ncbi.nlm.nih.gov/pubmed/28809922
http://dx.doi.org/10.1371/journal.pone.0181350

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