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Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation

BACKGROUND: Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study investigated the effects of hepatic nuclear factor (HNF) 4α o...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Cong, Min, Liu, Tianhui, Xu, Hufeng, Wang, Lin, Sun, Guangyong, Yang, Aiting, Zhang, Dong, Huang, Jian, Sun, Yameng, Zhao, Wenshan, Ma, Hong, Jia, Jidong, You, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557474/
https://www.ncbi.nlm.nih.gov/pubmed/28807057
http://dx.doi.org/10.1186/s13287-017-0629-8