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Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation
BACKGROUND: Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study investigated the effects of hepatic nuclear factor (HNF) 4α o...
Autores principales: | Wang, Ping, Cong, Min, Liu, Tianhui, Xu, Hufeng, Wang, Lin, Sun, Guangyong, Yang, Aiting, Zhang, Dong, Huang, Jian, Sun, Yameng, Zhao, Wenshan, Ma, Hong, Jia, Jidong, You, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557474/ https://www.ncbi.nlm.nih.gov/pubmed/28807057 http://dx.doi.org/10.1186/s13287-017-0629-8 |
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