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Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops

Claudins (Cldns) are transmembrane tight junction (TJ) proteins that paracellularly seal endo- and epithelial barriers by their interactions within the TJs. However, the mechanisms allowing TJ remodeling while maintaining barrier integrity are largely unknown. Cldns and occludin are heterophilically...

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Detalles Bibliográficos
Autores principales: Gehne, Nora, Lamik, Agathe, Lehmann, Martin, Haseloff, Reiner F., Andjelkovic, Anuska V., Blasig, Ingolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557494/
https://www.ncbi.nlm.nih.gov/pubmed/28813441
http://dx.doi.org/10.1371/journal.pone.0182106