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“UPRegulation” of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses

We recently demonstrated that targeting the unfolded protein response (UPR) protein GRP78 down-regulates CD47 expression, resulting in increased tumor macrophage infiltration and inhibited resistance to anti-estrogen therapy. We now show new data indicating that anti-estrogen therapy regulates CD47...

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Detalles Bibliográficos
Autores principales: Cook, Katherine L., Soto-Pantoja, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557514/
https://www.ncbi.nlm.nih.gov/pubmed/28815041
http://dx.doi.org/10.1186/s40364-017-0105-8