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“UPRegulation” of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses
We recently demonstrated that targeting the unfolded protein response (UPR) protein GRP78 down-regulates CD47 expression, resulting in increased tumor macrophage infiltration and inhibited resistance to anti-estrogen therapy. We now show new data indicating that anti-estrogen therapy regulates CD47...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557514/ https://www.ncbi.nlm.nih.gov/pubmed/28815041 http://dx.doi.org/10.1186/s40364-017-0105-8 |