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Analysis of AgoshRNA maturation and loading into Ago2

The RNA interference (RNAi) pathway was recently expanded by the discovery of multiple alternative pathways for processing of natural microRNA (miRNA) and man-made short hairpin RNA (shRNA) molecules. One non-canonical pathway bypasses Dicer cleavage and requires instead processing by Argonaute2 (Ag...

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Detalles Bibliográficos
Autores principales: Harwig, Alex, Kruize, Zita, Yang, Zhenhuang, Restle, Tobias, Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557517/
https://www.ncbi.nlm.nih.gov/pubmed/28809941
http://dx.doi.org/10.1371/journal.pone.0183269