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Understanding the cluster randomised crossover design: a graphical illustraton of the components of variation and a sample size tutorial
BACKGROUND: In a cluster randomised crossover (CRXO) design, a sequence of interventions is assigned to a group, or ‘cluster’ of individuals. Each cluster receives each intervention in a separate period of time, forming ‘cluster-periods’. Sample size calculations for CRXO trials need to account for...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557529/ https://www.ncbi.nlm.nih.gov/pubmed/28810895 http://dx.doi.org/10.1186/s13063-017-2113-2 |