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A tandem simulation framework for predicting mapping quality

Read alignment is the first step in most sequencing data analyses. Because a read’s point of origin can be ambiguous, aligners report a mapping quality, which is the probability that the reported alignment is incorrect. Despite its importance, there is no established and general method for calculati...

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Detalles Bibliográficos
Autor principal: Langmead, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557537/
https://www.ncbi.nlm.nih.gov/pubmed/28806977
http://dx.doi.org/10.1186/s13059-017-1290-3