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A tandem simulation framework for predicting mapping quality
Read alignment is the first step in most sequencing data analyses. Because a read’s point of origin can be ambiguous, aligners report a mapping quality, which is the probability that the reported alignment is incorrect. Despite its importance, there is no established and general method for calculati...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557537/ https://www.ncbi.nlm.nih.gov/pubmed/28806977 http://dx.doi.org/10.1186/s13059-017-1290-3 |