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REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles of the eNOS/NO/cGMP pathway and supplementation with L-arginine

Sleep loss can induce or aggravate the development of cardiovascular and cerebrovascular diseases. However, the molecular mechanism underlying this phenomenon is poorly understood. The present study was designed to investigate the effects of REM sleep deprivation on blood pressure in rats and the un...

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Detalles Bibliográficos
Autores principales: Jiang, Jiaye, Gan, Zhongyuan, Li, Yuan, Zhao, Wenqi, Li, Hanqing, Zheng, Jian-Pu, Ke, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557538/
https://www.ncbi.nlm.nih.gov/pubmed/28809932
http://dx.doi.org/10.1371/journal.pone.0182746