Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors

Malignant peripheral nerve sheath tumors (MPNST) are rare, highly aggressive sarcomas that can occur spontaneously or from pre-existing plexiform neurofibromas in neurofibromatosis type1 (NF1) patients. MPNSTs have high local recurrence rates, metastasize easily, are generally resistant to therapeut...

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Detalles Bibliográficos
Autores principales: Amirnasr, Azadeh, Verdijk, Rob M., van Kuijk, Patricia F., Taal, Walter, Sleijfer, Stefan, Wiemer, Erik A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557548/
https://www.ncbi.nlm.nih.gov/pubmed/28813519
http://dx.doi.org/10.1371/journal.pone.0183155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557548/
https://www.ncbi.nlm.nih.gov/pubmed/28813519
http://dx.doi.org/10.1371/journal.pone.0183155

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