Role of metabolites of cyclophosphamide in cardiotoxicity

BACKGROUND: The dose-limiting toxic effect of cyclophosphamide (CY) is cardiotoxicity. The pathogenesis of myocardial damage is poorly understood, and there is no established means of prevention. In previous studies, we suggested that for CY-induced cardiotoxicity, whereas acrolein is the key toxic...

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Detalles Bibliográficos
Autores principales: Kurauchi, Koichiro, Nishikawa, Takuro, Miyahara, Emiko, Okamoto, Yasuhiro, Kawano, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557551/
https://www.ncbi.nlm.nih.gov/pubmed/28807058
http://dx.doi.org/10.1186/s13104-017-2726-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557551/
https://www.ncbi.nlm.nih.gov/pubmed/28807058
http://dx.doi.org/10.1186/s13104-017-2726-2

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