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Pharmacokinetic and urinary profiling reveals the prednisolone/cortisol ratio as a valid biomarker for prednisolone administration

BACKGROUND: In Europe, synthetic corticosteroids are not allowed in animal breeding for growth-promoting purposes. Nevertheless, a high prevalence of non-compliant urine samples was recently reported for prednisolone, however, without any indication of unauthorized use. Within this context, 20β-dihy...

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Detalles Bibliográficos
Autores principales: Van Meulebroek, Lieven, De Clercq, Nathalie, Vanden Bussche, Julie, Devreese, Mathias, Fichant, Eric, Delahaut, Philippe, Croubels, Siska, Vanhaecke, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557569/
https://www.ncbi.nlm.nih.gov/pubmed/28806969
http://dx.doi.org/10.1186/s12917-017-1158-5