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ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats

OBJECTIVE: ET-26 HCl is a promising sedative–hypnotic anesthetic with virtually no effect on adrenocortical steroid synthesis. However, whether or not ET-26 HCl also has a sufficiently wide safety margin and hemodynamic stability similar to that of etomidate and related compounds remains unknown. In...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Chen, Shouming, Yang, Jun, Yang, Linghui, Liu, Jin, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557577/
https://www.ncbi.nlm.nih.gov/pubmed/28813523
http://dx.doi.org/10.1371/journal.pone.0183439