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Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration

Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A(3) (HXA(3)), initiating neutrophil transepithelial migration. Migrated neutrophils amp...

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Detalles Bibliográficos
Autores principales: Pazos, Michael A., Lanter, Bernard B., Yonker, Lael M., Eaton, Alex D., Pirzai, Waheed, Gronert, Karsten, Bonventre, Joseph V., Hurley, Bryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557605/
https://www.ncbi.nlm.nih.gov/pubmed/28771621
http://dx.doi.org/10.1371/journal.ppat.1006548