Cargando…

Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration

Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A(3) (HXA(3)), initiating neutrophil transepithelial migration. Migrated neutrophils amp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pazos, Michael A., Lanter, Bernard B., Yonker, Lael M., Eaton, Alex D., Pirzai, Waheed, Gronert, Karsten, Bonventre, Joseph V., Hurley, Bryan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557605/ https://www.ncbi.nlm.nih.gov/pubmed/28771621 http://dx.doi.org/10.1371/journal.ppat.1006548

Ejemplares similares

The Population Structure of Pseudomonas aeruginosa Is Characterized by Genetic Isolation of exoU+ and exoS+ Lineages
por: Ozer, Egon A, et al.
Publicado: (2019)

Association between possession of ExoU and antibiotic resistance in Pseudomonas aeruginosa
por: Subedi, Dinesh, et al.
Publicado: (2018)

Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia
por: Howell, Heather A., et al.
Publicado: (2013)

Pseudomonas aeruginosa Type III Secretory Toxin ExoU and Its Predicted Homologs
por: Sawa, Teiji, et al.
Publicado: (2016)

Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections
por: Foulkes, Daniel M., et al.
Publicado: (2019)

Pseudomonas aeruginosa ExoU-associated virulence in HCT recipients and patients with hematologic malignancies
por: Fontana, Lauren, et al.
Publicado: (2023)

Presence of exoY, exoS, exoU and exoT genes, antibiotic resistance and biofilm production among Pseudomonas aeruginosa isolates in Northwest Iran
por: Azimi, Somayeh, et al.
Publicado: (2016)

Emergence of ST463 exoU-Positive, Imipenem-Nonsusceptible Pseudomonas aeruginosa Isolates in China
por: Zhu, Ying, et al.
Publicado: (2023)

Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa
por: Gendrin, Claire, et al.
Publicado: (2012)

ExoU-induced redox imbalance and oxidative stress in airway epithelial cells during Pseudomonas aeruginosa pneumosepsis
por: da Cunha, Luiz Gonzaga, et al.
Publicado: (2015)

Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology
por: Bagayoko, Salimata, et al.
Publicado: (2021)

ExoU Activates NF-κB and Increases IL-8/KC Secretion during Pseudomonas aeruginosa Infection
por: de Lima, Carolina Diettrich Mallet, et al.
Publicado: (2012)

High frequency of the exoU+/exoS+ genotype associated with multidrug-resistant “high-risk clones” of Pseudomonas aeruginosa clinical isolates from Peruvian hospitals
por: Horna, Gertrudis, et al.
Publicado: (2019)

Phenotypic and Genomic Comparison of the Two Most Common ExoU-Positive Pseudomonas aeruginosa Clones, PA14 and ST235
por: Fischer, Sebastian, et al.
Publicado: (2020)

ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during Pseudomonas aeruginosa Infection
por: Hardy, Kierra S., et al.
Publicado: (2022)

Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection
por: Hardy, Kierra S., et al.
Publicado: (2021)

Utilizing in silico and in vitro methods to identify possible binding sites of a novel ligand against Pseudomonas aeruginosa phospholipase toxin ExoU
por: Chamberlain, Krista, et al.
Publicado: (2021)

Characterization of the ExoU activation mechanism using EPR and integrative modeling
por: Tessmer, Maxx H., et al.
Publicado: (2020)

The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model
por: Hardy, Kierra S., et al.
Publicado: (2022)

The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
por: Deruelle, Vincent, et al.
Publicado: (2021)

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU
por: Halavaty, Andrei S., et al.
Publicado: (2012)

Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis
por: Machado, Gloria-Beatriz, et al.
Publicado: (2011)

The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia
por: Rangel, Stephanie M., et al.
Publicado: (2015)

Correction: The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia
por: Rangel, Stephanie M., et al.
Publicado: (2015)

Structure and Dynamics of Type III Secretion Effector Protein ExoU As determined by SDSL-EPR Spectroscopy in Conjunction with De Novo Protein Folding
por: Fischer, Axel W., et al.
Publicado: (2017)

The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model
por: Kloth, Christina, et al.
Publicado: (2018)

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
por: Belyy, Alexander, et al.
Publicado: (2016)

Epithelial permeability and the transepithelial migration of human neutrophils
Publicado: (1983)

Intoxication of Host Cells by the T3SS Phospholipase ExoU: PI(4,5)P(2)-Associated, Cytoskeletal Collapse and Late Phase Membrane Blebbing
por: Sato, Hiromi, et al.
Publicado: (2014)

Characterization of exo-s, exo-u, and alg virulence factors and antimicrobial resistance in Pseudomonas aeruginosa isolated from migratory Egyptian vultures from India
por: Sharma, Pradeep, et al.
Publicado: (2014)

The effector protein ExoY secreted by Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for GTP
por: Voigt, Ulrike, et al.
Publicado: (2011)

The ADP-Ribosyltransferase Domain of the Effector Protein ExoS Inhibits Phagocytosis of Pseudomonas aeruginosa during Pneumonia
por: Rangel, Stephanie M., et al.
Publicado: (2014)

Pseudomonas aeruginosa ExoY, a cyclic GMP- and cyclic UMP-generating nucleotidyl cyclase
por: Seifert, Roland, et al.
Publicado: (2013)

The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates
por: Munder, Antje, et al.
Publicado: (2018)

Effect of subinhibitory concentrations of imipenem and piperacillin on Pseudomonas aeruginosa toxA and exoS transcriptional expression
por: Haghi, F., et al.
Publicado: (2019)

High‐throughput dilution‐based growth method enables time‐resolved exo‐metabolomics of Pseudomonas putida and Pseudomonas aeruginosa
por: Pedersen, Bjarke H., et al.
Publicado: (2021)

Illuminating dynamic neutrophil trans-epithelial migration with micro-optical coherence tomography
por: Chu, Kengyeh K., et al.
Publicado: (2017)

Epithelial exposure to hypoxia modulates neutrophil transepithelial migration
Publicado: (1996)

Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium
por: Hurley, Bryan P., et al.
Publicado: (2019)

Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells
por: Silistre, Hazel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0nrvm83h4j26kso727464qugm2