Mild and Regioselective Pd(OAc)(2)-Catalyzed C–H Arylation of Tryptophans by [ArN(2)]X, Promoted by Tosic Acid

[Image: see text] A regioselective Pd-mediated C–H bond arylation methodology for tryptophans, utilizing stable aryldiazonium salts, affords C2-arylated tryptophan derivatives, in several cases quantitatively. The reactions proceed in air, without base, and at room temperature in EtOAc. The syntheti...

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Detalles Bibliográficos
Autores principales: Reay, Alan J., Hammarback, L. Anders, Bray, Joshua T. W., Sheridan, Thomas, Turnbull, David, Whitwood, Adrian C., Fairlamb, Ian J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557615/
https://www.ncbi.nlm.nih.gov/pubmed/28824821
http://dx.doi.org/10.1021/acscatal.6b03121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557615/
https://www.ncbi.nlm.nih.gov/pubmed/28824821
http://dx.doi.org/10.1021/acscatal.6b03121

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