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Co-delivery nanocarriers targeting folate receptor and encapsulating 2-deoxyglucose and α-tocopheryl succinate enhance anti-tumor effect in vivo

A combination administration of chemical agents was highlighted to treat tumors. Recently, tumor cell has been found to be different from normal cell in metabolic manner. Most of cancer cells prefer aerobic glycolysis to mitochondrial oxidative phosphorylation (OXPHOS) to satisfy energy and biomass...

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Detalles Bibliográficos
Autores principales: Lei, Xiaoying, Li, Ke, Liu, Yan, Wang, Zhen Yu, Ruan, Ban Jun, Wang, Li, Xiang, An, Wu, Daocheng, Lu, Zifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557622/
https://www.ncbi.nlm.nih.gov/pubmed/28848348
http://dx.doi.org/10.2147/IJN.S135849