Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs – method development and application to magnesium in sheep

BACKGROUND: There have been few reports of pharmacokinetic models that have been linked to models of the cardiovascular system. Such models could predict the cardiovascular effects of a drug under a variety of circumstances. Limiting factors may be the lack of a suitably simple cardiovascular model,...

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Detalles Bibliográficos
Autores principales: Upton, Richard N, Ludbrook, Guy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555767/
https://www.ncbi.nlm.nih.gov/pubmed/15760466
http://dx.doi.org/10.1186/1471-2210-5-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555767/
https://www.ncbi.nlm.nih.gov/pubmed/15760466
http://dx.doi.org/10.1186/1471-2210-5-5

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