DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway

DT-13(25(R,S)-ruscogenin-1-O-[β-d-glucopyranosyl-(1→2)][β-d-xylopyranosyl-(1→3)]-β-d-fucopyranoside) has been identified as an important factor in TNF-α-induced vascular inflammation. However, the effect of DT-13 on TNF-α-induced endothelial permeability and the potential molecular mechanisms remain...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Han, Yuwei, Zhao, Yazheng, Lv, Yanni, Hu, Yang, Tan, Yisha, Bi, Xueyuan, Yu, Boyang, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557769/
https://www.ncbi.nlm.nih.gov/pubmed/28855900
http://dx.doi.org/10.3389/fimmu.2017.00925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557769/
https://www.ncbi.nlm.nih.gov/pubmed/28855900
http://dx.doi.org/10.3389/fimmu.2017.00925

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