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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Autoimmune hemolytic anemia (AIHA) is a potentially severe disease in which red blood cells (RBC) are destroyed by IgG anti-RBC autoantibodies which can lead to hemolysis. We recently found IgG Fc-glycosylation towards platelet and RBC alloantigens to be skewed towards decreased fucosylation, increa...

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Detalles Bibliográficos
Autores principales: Sonneveld, Myrthe E., de Haas, Masja, Koeleman, Carolien, de Haan, Noortje, Zeerleder, Sacha S., Ligthart, Peter C., Wuhrer, Manfred, van der Schoot, C. Ellen, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557851/
https://www.ncbi.nlm.nih.gov/pubmed/28811589
http://dx.doi.org/10.1038/s41598-017-08654-y