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Characterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates

Despite the mitochondrial antiviral signalling protein (MAVS)-dependent RIG-I-like receptor (RLR) signalling pathway in the cytosol plays an indispensable role in the antiviral immunity of the host, surprising little is known in invertebrates. Here we characterized the major members of RLR pathway a...

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Detalles Bibliográficos
Autores principales: Huang, Baoyu, Zhang, Linlin, Du, Yishuai, Xu, Fei, Li, Li, Zhang, Guofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557890/
https://www.ncbi.nlm.nih.gov/pubmed/28811654
http://dx.doi.org/10.1038/s41598-017-08566-x