Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

DNA polymerase (pol) μ is a DNA-dependent polymerase that incorporates nucleotides during gap-filling synthesis in the non-homologous end-joining pathway of double-strand break repair. Here we report time-lapse X-ray crystallography snapshots of catalytic events during gap-filling DNA synthesis by p...

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Detalles Bibliográficos
Autores principales: Jamsen, Joonas A., Beard, William A., Pedersen, Lars C., Shock, David D., Moon, Andrea F., Krahn, Juno M., Bebenek, Katarzyna, Kunkel, Thomas A., Wilson, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557891/
https://www.ncbi.nlm.nih.gov/pubmed/28811466
http://dx.doi.org/10.1038/s41467-017-00271-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557891/
https://www.ncbi.nlm.nih.gov/pubmed/28811466
http://dx.doi.org/10.1038/s41467-017-00271-7

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