Overexpressed somatic alleles are enriched in functional elements in Breast Cancer

Asymmetric allele content in the transcriptome can be indicative of functional and selective features of the underlying genetic variants. Yet, imbalanced alleles, especially from diploid genome regions, are poorly explored in cancer. Here we systematically quantify and integrate the variant allele f...

Descripción completa

Detalles Bibliográficos
Autores principales: Restrepo, Paula, Movassagh, Mercedeh, Alomran, Nawaf, Miller, Christian, Li, Muzi, Trenkov, Chris, Manchev, Yulian, Bahl, Sonali, Warnken, Stephanie, Spurr, Liam, Apanasovich, Tatiyana, Crandall, Keith, Edwards, Nathan, Horvath, Anelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557904/
https://www.ncbi.nlm.nih.gov/pubmed/28811643
http://dx.doi.org/10.1038/s41598-017-08416-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557904/
https://www.ncbi.nlm.nih.gov/pubmed/28811643
http://dx.doi.org/10.1038/s41598-017-08416-w

Ejemplares similares