Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

Antiviral treatment options for chronic Hepatitis E Virus (HEV) infections are limited and immunological determinants of viral persistence remain largely unexplored. We studied the antiviral potency of pegylated interferon-α (pegIFNα) against HEV infections in humanized mice and modelled intrahepati...

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Detalles Bibliográficos
Autores principales: van de Garde, Martijn D. B., Pas, Suzan D., van Oord, Gertine W., Gama, Lucio, Choi, Youkyung, de Man, Robert A., Boonstra, Andre, Vanwolleghem, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557905/
https://www.ncbi.nlm.nih.gov/pubmed/28811492
http://dx.doi.org/10.1038/s41598-017-07434-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557905/
https://www.ncbi.nlm.nih.gov/pubmed/28811492
http://dx.doi.org/10.1038/s41598-017-07434-y

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