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A Phase I trial using local regional treatment, nonlethal irradiation, intratumoral and systemic polyinosinic-polycytidylic acid polylysine carboxymethylcellulose to treat liver cancer: in search of the abscopal effect

PURPOSE: To determine the safety of an approach to immunologically enhance local treatment of hepatocellular cancer (HCC) by combining nonlethal radiation, local regional therapy with intratumoral injection, and systemic administration of a potent Toll-like receptor (TLR) immune adjuvant. METHODS: P...

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Detalles Bibliográficos
Autores principales: de la Torre, Andrew N, Contractor, Sohail, Castaneda, Ismael, Cathcart, Charles S, Razdan, Dolly, Klyde, David, Kisza, Piotr, Gonzales, Sharon F, Salazar, Andres M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557908/
https://www.ncbi.nlm.nih.gov/pubmed/28848723
http://dx.doi.org/10.2147/JHC.S136652