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A Phase I trial using local regional treatment, nonlethal irradiation, intratumoral and systemic polyinosinic-polycytidylic acid polylysine carboxymethylcellulose to treat liver cancer: in search of the abscopal effect
PURPOSE: To determine the safety of an approach to immunologically enhance local treatment of hepatocellular cancer (HCC) by combining nonlethal radiation, local regional therapy with intratumoral injection, and systemic administration of a potent Toll-like receptor (TLR) immune adjuvant. METHODS: P...
Autores principales: | de la Torre, Andrew N, Contractor, Sohail, Castaneda, Ismael, Cathcart, Charles S, Razdan, Dolly, Klyde, David, Kisza, Piotr, Gonzales, Sharon F, Salazar, Andres M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557908/ https://www.ncbi.nlm.nih.gov/pubmed/28848723 http://dx.doi.org/10.2147/JHC.S136652 |
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