High-fat diet-induced acceleration of osteoarthritis is associated with a distinct and sustained plasma metabolite signature

Metabolic changes induced by high fat diet (HFD) that contribute to osteoarthritis (OA) are poorly understood. We investigated longitudinal changes to metabolites and their contribution to OA pathogenesis in response to HFD. HFD-fed mice exhibited acceleration of spontaneous age-related and surgical...

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Detalles Bibliográficos
Autores principales: Datta, Poulami, Zhang, Yue, Parousis, Alexa, Sharma, Anirudh, Rossomacha, Evgeny, Endisha, Helal, Wu, Brian, Kacprzak, Izabela, Mahomed, Nizar N., Gandhi, Rajiv, Rockel, Jason S., Kapoor, Mohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557929/
https://www.ncbi.nlm.nih.gov/pubmed/28811491
http://dx.doi.org/10.1038/s41598-017-07963-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557929/
https://www.ncbi.nlm.nih.gov/pubmed/28811491
http://dx.doi.org/10.1038/s41598-017-07963-6

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