RGD delivery of truncated coagulase to tumor vasculature affords local thrombotic activity to induce infarction of tumors in mice

Induction of thrombosis in tumor vasculature represents an appealing strategy for combating cancer. Herein, we combined unique intrinsic coagulation properties of staphylocoagulase with new acquired functional potentials introduced by genetic engineering, to generate a novel bi-functional fusion pro...

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Detalles Bibliográficos
Autores principales: Jahanban-Esfahlan, Rana, Seidi, Khaled, Monhemi, Hassan, Adli, Amir Daei Farshchi, Minofar, Babak, Zare, Peyman, Farajzadeh, Davoud, Farajnia, Safar, Behzadi, Ramezan, Abbasi, Mehran Mesgari, Zarghami, Nosratollah, Javaheri, Tahereh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557930/
https://www.ncbi.nlm.nih.gov/pubmed/28811469
http://dx.doi.org/10.1038/s41598-017-05326-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557930/
https://www.ncbi.nlm.nih.gov/pubmed/28811469
http://dx.doi.org/10.1038/s41598-017-05326-9

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