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Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Aging is a complex biological process regulated by multiple cellular pathways and molecular mechanisms including epigenetics. Using genome-wide DNA methylation data measured in a large collection of Scottish old individuals, we performed discovery association analysis to identify age-methylated CpGs...

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Detalles Bibliográficos
Autores principales: Li, Shuxia, Christiansen, Lene, Christensen, Kaare, Kruse, Torben A., Redmond, Paul, Marioni, Riccardo E., Deary, Ian J., Tan, Qihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557932/
https://www.ncbi.nlm.nih.gov/pubmed/28811542
http://dx.doi.org/10.1038/s41598-017-08346-7