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Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells

MYST histone acetyltransferases have crucial functions in transcription, replication and DNA repair and are hence implicated in development and cancer. Here we characterise Myst2/Kat7/Hbo1 protein interactions in mouse embryonic stem cells by affinity purification coupled to mass spectrometry. This...

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Detalles Bibliográficos
Autores principales: Pardo, Mercedes, Yu, Lu, Shen, Shihpei, Tate, Peri, Bode, Daniel, Letney, Blake L., Quelle, Dawn E., Skarnes, William, Choudhary, Jyoti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557939/
https://www.ncbi.nlm.nih.gov/pubmed/28811661
http://dx.doi.org/10.1038/s41598-017-08456-2