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Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals

Morbidly obese patients exhibit impaired secretion of gut hormones that may contribute to the development of obesity. After bariatric surgery there is a dramatic increase in gut hormone release. In this study, gastric and duodenal tissues were endoscopically collected from lean, and morbidly obese s...

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Detalles Bibliográficos
Autores principales: Wölnerhanssen, Bettina K., Moran, Andrew W., Burdyga, Galina, Meyer-Gerspach, Anne Christin, Peterli, Ralph, Manz, Michael, Thumshirn, Miriam, Daly, Kristian, Beglinger, Christoph, Shirazi-Beechey, Soraya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557953/
https://www.ncbi.nlm.nih.gov/pubmed/28811552
http://dx.doi.org/10.1038/s41598-017-08487-9