Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner

Prenatal hypoxia is associated with growth restriction and adverse cardiovascular outcomes. Here, we describe renal and cardiovascular outcomes in ageing mouse offspring prenatally exposed to hypoxia (12% O(2)) from embryonic day 14.5 until birth. At 12 months of age, both male and female offspring...

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Detalles Bibliográficos
Autores principales: Walton, S. L., Bielefeldt-Ohmann, H., Singh, R. R., Li, J., Paravicini, T. M., Little, M. H., Moritz, K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557956/
https://www.ncbi.nlm.nih.gov/pubmed/28811528
http://dx.doi.org/10.1038/s41598-017-08365-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557956/
https://www.ncbi.nlm.nih.gov/pubmed/28811528
http://dx.doi.org/10.1038/s41598-017-08365-4

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