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Transcriptional response to stress is pre-wired by promoter and enhancer architecture

Programs of gene expression are executed by a battery of transcription factors that coordinate divergent transcription from a pair of tightly linked core initiation regions of promoters and enhancers. Here, to investigate how divergent transcription is reprogrammed upon stress, we measured nascent R...

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Detalles Bibliográficos
Autores principales: Vihervaara, Anniina, Mahat, Dig Bijay, Guertin, Michael J., Chu, Tinyi, Danko, Charles G., Lis, John T., Sistonen, Lea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557961/
https://www.ncbi.nlm.nih.gov/pubmed/28811569
http://dx.doi.org/10.1038/s41467-017-00151-0