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Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents

In the last two decades, the repertoire of clinically effective antibacterials is shrinking due to the rapidly increasing of multi-drug-resistant pathogenic bacteria. New chemical classes with innovative mode of action are required to prevent a return to the pre-antibiotic era. We have recently repo...

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Detalles Bibliográficos
Autores principales: Zamperini, C., Maccari, G., Deodato, D., Pasero, C., D’Agostino, I., Orofino, F., De Luca, F., Dreassi, E., Docquier, J. D., Botta, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557985/
https://www.ncbi.nlm.nih.gov/pubmed/28811659
http://dx.doi.org/10.1038/s41598-017-08749-6