Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality

The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2-sulfo-N-acetylneuraminic acid and its 4-deoxy-3,4-dehydrog...

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Detalles Bibliográficos
Autores principales: Vavricka, Christopher J., Muto, Chiaki, Hasunuma, Tomohisa, Kimura, Yoshinobu, Araki, Michihiro, Wu, Yan, Gao, George F., Ohrui, Hiroshi, Izumi, Minoru, Kiyota, Hiromasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557986/
https://www.ncbi.nlm.nih.gov/pubmed/28811524
http://dx.doi.org/10.1038/s41598-017-07836-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557986/
https://www.ncbi.nlm.nih.gov/pubmed/28811524
http://dx.doi.org/10.1038/s41598-017-07836-y

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