An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in Sprague-Dawley rats. The...

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Detalles Bibliográficos
Autores principales: Kim, Martha, Park, Joo-Hee, Jeong, Hyejoong, Hong, Jinkee, Choi, Woo Sung, Lee, Byung-Han, Park, Choul Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557988/
https://www.ncbi.nlm.nih.gov/pubmed/28811672
http://dx.doi.org/10.1038/s41598-017-08843-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557988/
https://www.ncbi.nlm.nih.gov/pubmed/28811672
http://dx.doi.org/10.1038/s41598-017-08843-9

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