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Bioconductor workflow for single-cell RNA sequencing: Normalization, dimensionality reduction, clustering, and lineage inference

Novel single-cell transcriptome sequencing assays allow researchers to measure gene expression levels at the resolution of single cells and offer the unprecendented opportunity to investigate at the molecular level fundamental biological questions, such as stem cell differentiation or the discovery...

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Detalles Bibliográficos
Autores principales: Perraudeau, Fanny, Risso, Davide, Street, Kelly, Purdom, Elizabeth, Dudoit, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558107/
https://www.ncbi.nlm.nih.gov/pubmed/28868140
http://dx.doi.org/10.12688/f1000research.12122.1