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Everolimus halts hepatic cystogenesis in a rodent model of polycystic-liver-disease

AIM: To develop a MRI-based method for accurate determination of liver volume (LV) and to explore the effect of long-term everolimus (EVR) treatment on LV in PCK rats with hepatomegaly. METHODS: Thirty-one female PCK rats (model for polycystic-liver-disease: PCLD) were randomized into 3 groups and t...

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Detalles Bibliográficos
Autores principales: Temmerman, Frederik, Chen, Feng, Libbrecht, Louis, Vander Elst, Ingrid, Windmolders, Petra, Feng, Yuanbo, Ni, Yicheng, De Smedt, Humbert, Nevens, Frederik, van Pelt, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558113/
https://www.ncbi.nlm.nih.gov/pubmed/28852309
http://dx.doi.org/10.3748/wjg.v23.i30.5499