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Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening
[Image: see text] Microfluidic droplet-based screening of DNA-encoded one-bead-one-compound combinatorial libraries is a miniaturized, potentially widely distributable approach to small molecule discovery. In these screens, a microfluidic circuit distributes library beads into droplets of activity a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558193/ https://www.ncbi.nlm.nih.gov/pubmed/28682059 http://dx.doi.org/10.1021/acscombsci.7b00061 |