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Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening

[Image: see text] Microfluidic droplet-based screening of DNA-encoded one-bead-one-compound combinatorial libraries is a miniaturized, potentially widely distributable approach to small molecule discovery. In these screens, a microfluidic circuit distributes library beads into droplets of activity a...

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Detalles Bibliográficos
Autores principales:	MacConnell, Andrew B., Paegel, Brian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558193/ https://www.ncbi.nlm.nih.gov/pubmed/28682059 http://dx.doi.org/10.1021/acscombsci.7b00061

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