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Clathrin-mediated post-fusion membrane retrieval influences the exocytic mode of endothelial Weibel-Palade bodies

Weibel-Palade bodies (WPBs), the storage organelles of endothelial cells, are essential to normal haemostatic and inflammatory responses. Their major constituent protein is von Willebrand factor (VWF) which, following stimulation with secretagogues, is released into the blood vessel lumen as large p...

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Detalles Bibliográficos
Autores principales: Stevenson, Nicola L., White, Ian J., McCormack, Jessica J., Robinson, Christopher, Cutler, Daniel F., Nightingale, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558267/
https://www.ncbi.nlm.nih.gov/pubmed/28674075
http://dx.doi.org/10.1242/jcs.200840