Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

Cells adapt to an exposure to xenobiotics by upregulating the biosynthesis of proteins involved in xenobiotic metabolism. This is achieved largely via activation of cellular xenosensors that modulate gene expression. Biotransformation of xenobiotics frequently comes with the generation of reactive o...

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Detalles Bibliográficos
Autores principales: Klotz, Lars-Oliver, Steinbrenner, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Short Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558470/
https://www.ncbi.nlm.nih.gov/pubmed/28818793
http://dx.doi.org/10.1016/j.redox.2017.07.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558470/
https://www.ncbi.nlm.nih.gov/pubmed/28818793
http://dx.doi.org/10.1016/j.redox.2017.07.015

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