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Self-Assembly DNA Polyplex Vaccine inside Dissolving Microneedles for High-Potency Intradermal Vaccination

The strong immunogenicity induction is the powerful weapon to prevent the virus infections. This study demonstrated that one-step synthesis of DNA polyplex vaccine in microneedle (MN) patches can induce high immunogenicity through intradermal vaccination and increase the vaccine stability for storag...

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Detalles Bibliográficos
Autores principales: Liao, Jing-Fong, Lee, Jin-Ching, Lin, Chun-Kuang, Wei, Kuo-Chen, Chen, Pin-Yuan, Yang, Hung-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558555/
https://www.ncbi.nlm.nih.gov/pubmed/28819449
http://dx.doi.org/10.7150/thno.19894