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The chemokine fractalkine (CX3CL1) attenuates H(2)O(2)-induced demyelination in cerebellar slices

BACKGROUND: Fractalkine/CX3CR1 signalling has been implicated in many neurodegenerative and neurological diseases of the central nervous system (CNS). This signalling pathway plays an important role in regulating reactive oxygen species (ROS), as well as itself being altered in conditions of oxidati...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Sinead A., Dev, Kumlesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558650/
https://www.ncbi.nlm.nih.gov/pubmed/28810923
http://dx.doi.org/10.1186/s12974-017-0932-4