CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

BACKGROUND: Oral squamous cell carcinoma (OSCC) is usually diagnosed at an advanced stage and is commonly preceded by oral premalignant lesions. The mortality rates have remained unchanged (50% within 5 years after diagnosis), and it is related to tobacco smoking and alcohol intake. Novel molecular...

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Detalles Bibliográficos
Autores principales: Morandi, Luca, Gissi, Davide, Tarsitano, Achille, Asioli, Sofia, Gabusi, Andrea, Marchetti, Claudio, Montebugnoli, Lucio, Foschini, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558660/
https://www.ncbi.nlm.nih.gov/pubmed/28814981
http://dx.doi.org/10.1186/s13148-017-0386-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558660/
https://www.ncbi.nlm.nih.gov/pubmed/28814981
http://dx.doi.org/10.1186/s13148-017-0386-7

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